Levofloxacin-based triple regimens were better than standard quadruple regimens for second-line eradication of Helicobacter pylori.

I n t e r v e n t i o n 70 patients each were allocated to 4 treatments: 1) a 10-day course of once-daily levofloxacin, 500 mg; twice-daily amoxicillin, 1 g; twice-daily rabeprazole, 20 mg (LAR); 2) a 10-day course of once-daily levofloxacin, 500 mg; twice-daily tinidazole, 500 mg; and twice-daily rabeprazole, 20 mg (LTR); 3) a 7-day course of 4 times daily tetracycline, 500 mg; 3 times daily metronidazole, 500 mg; 4 times daily bismuth salt, 120 mg; and twice-daily rebepraxole, 20 mg (7TMBR); or 4) a 14-day course of TMBR (14TMBR).